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6PYF

Sex Hormone-binding globulin mutant E176K in complex with Estradiol

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Sex hormone-binding globulinpolymer20522610.71UniProt (P04278)
Pfam (PF00054)
Homo sapiens (Human)SHBG,Sex steroid-binding protein,SBP,Testis-specific androgen-binding protein,ABP,Testosterone-estradiol-binding globulin,TeBG,Testosterone-estrogen-binding globulin
2B
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
3C
(A)
ESTRADIOLnon-polymer272.41Chemie (EST)
4D
(A)
waterwater18.0186Chemie (HOH)
Sequence modifications
A: 1 - 205 (UniProt: P04278)
PDBExternal DatabaseDetails
Lys 176Glu 205engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight22610.7
Non-Polymers*Number of molecules2
Total formula weight312.5
All*Total formula weight22923.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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