6PYF
Sex Hormone-binding globulin mutant E176K in complex with Estradiol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sex hormone-binding globulin | polymer | 205 | 22610.7 | 1 | UniProt (P04278) Pfam (PF00054) | Homo sapiens (Human) | SHBG,Sex steroid-binding protein,SBP,Testis-specific androgen-binding protein,ABP,Testosterone-estradiol-binding globulin,TeBG,Testosterone-estrogen-binding globulin |
| 2 | B (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) PubChem (271) | |||
| 3 | C (A) | ESTRADIOL | non-polymer | 272.4 | 1 | Chemie (EST) PubChem (16757676) PubChem (1807201) PubChem (450) PubChem (177015577) PubChem (5757) PubChem (5998) PubChem (10596) PubChem (14880) PubChem (43912931) PubChem (44284023) PubChem (68570) PubChem (46781508) PubChem (54403267) PubChem (56624791) PubChem (57041922) PubChem (58650893) PubChem (59084698) PubChem (1807200) PubChem (68014581) PubChem (68209947) PubChem (70220248) PubChem (70864205) PubChem (667480) PubChem (667515) PubChem (721867) PubChem (928284) PubChem (1258565) PubChem (5317221) PubChem (91740223) PubChem (5317222) PubChem (5745505) PubChem (6328313) PubChem (6432565) PubChem (6560352) PubChem (6603846) PubChem (101691329) PubChem (6918968) PubChem (6919041) PubChem (7000012) PubChem (7004689) PubChem (7048584) PubChem (7048670) PubChem (118548795) PubChem (7061189) PubChem (7067800) PubChem (9795489) PubChem (9811784) PubChem (9903595) PubChem (9938293) PubChem (12313788) PubChem (11869602) PubChem (11870431) PubChem (12313787) PubChem (12313791) PubChem (12313794) PubChem (162947701) PubChem (166849971) PubChem (126969992) PubChem (129010410) PubChem (129317336) PubChem (130307439) PubChem (130307440) PubChem (143489158) PubChem (144605119) PubChem (145157829) PubChem (145610824) PubChem (154109755) PubChem (172873304) | |||
| 4 | D (A) | water | water | 18.0 | 186 | Chemie (HOH) |
Sequence modifications
A: 1 - 205 (UniProt: P04278)
| PDB | External Database | Details |
|---|---|---|
| Lys 176 | Glu 205 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22610.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 312.5 | |
| All* | Total formula weight | 22923.1 |
