6PXU
Crystal structure of human GalNAc-T12 bound to a diglycosylated peptide, Mn2+, and UDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Polypeptide N-acetylgalactosaminyltransferase 12 | polymer | 543 | 62739.0 | 2 | UniProt (Q8IXK2) Pfam (PF00535) Pfam (PF00652) | Homo sapiens (Human) | Polypeptide GalNAc transferase 12,pp-GaNTase 12,Protein-UDP acetylgalactosaminyltransferase 12,UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12 |
| 2 | C, D (C, D) | GAGATGAGAGYYITPRTGAGA | polymer | 21 | 1841.0 | 2 | synthetic construct | ||
| 3 | E, Q (A, B) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) | |||
| 4 | AA, BA, CA, F, G... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 12 | Chemie (EDO) | |||
| 5 | I, J, K, U, V... (A, B) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 6 | DA, N, O, P (B, A) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 7 | EA, FA, GA, HA (C, D) | 2-acetamido-2-deoxy-alpha-D-galactopyranose | non-polymer | 221.2 | 4 | Chemie (A2G) | |||
| 8 | IA, JA, KA, LA (A, B, C, D) | water | water | 18.0 | 562 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 129159.9 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 3394.5 | |
| All* | Total formula weight | 132554.4 |
