6PXJ
Crystal structure of human thrombin mutant I16T
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (L, A) | Thrombin light chain | polymer | 36 | 4096.5 | 2 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (Human) | Coagulation factor II |
| 2 | B, C (H, B) | Thrombin heavy chain | polymer | 259 | 29768.2 | 2 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (Human) | Coagulation factor II |
| 3 | E, F (H) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | G (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | H, I, J, K (L, H, B, A) | water | water | 18.0 | 463 | Chemie (HOH) |
Sequence modifications
H, B: 16 - 247 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| Thr 16 | Ile 364 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 67729.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 208.5 | |
| All* | Total formula weight | 67937.9 |
