6PXH
Crystal Structure of MERS-CoV S1-NTD bound with G2 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | MERS-CoV S1-NTD | polymer | 342 | 38382.0 | 2 | UniProt (V9TWK2) Pfam (PF16451) UniProt (by SIFTS) (K9N5Q8) | Middle East respiratory syndrome-related coronavirus | |
| 2 | C, E (C, H) | G2 heavy chain | polymer | 229 | 24275.1 | 2 | Mus musculus | ||
| 3 | D, F (D, L) | G2 light chain | polymer | 218 | 23861.3 | 2 | Mus musculus | ||
| 4 | G, H, I, M (E, F, G, M) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 4 | In PDB GlyTouCan (G15407YE) | |||
| 5 | J, L, N, P (I, K, N, P) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 6 | K (J) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1397.2 | 1 | In PDB GlyTouCan (G80966KZ) | |||
| 7 | O (O) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 8 | Q, R, X, Y, Z (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 9 | AA, BA, CA, EA, FA... (B, C, H, A) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 10 | DA, W (B, A) | DIHYDROFOLIC ACID | non-polymer | 443.4 | 2 | Chemie (DHF) | |||
| 11 | HA, IA, JA, KA, LA... (A, B, C, D, H...) | water | water | 18.0 | 685 | Chemie (HOH) |
Sequence modifications
A, B: 18 - 351 (UniProt: V9TWK2)
| PDB | External Database | Details |
|---|---|---|
| Gly 352 | - | expression tag |
| Ser 353 | - | expression tag |
| Leu 354 | - | expression tag |
| Glu 355 | - | expression tag |
| Val 356 | - | expression tag |
| Leu 357 | - | expression tag |
| Phe 358 | - | expression tag |
| Gln 359 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 173036.7 | |
| Branched | Number of molecules | 10 |
| Total formula weight | 6351.8 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2953.5 | |
| All* | Total formula weight | 182342.0 |
