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6PX1

Set2 bound to nucleosome

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(A, E)
Histone H3polymer13615437.12UniProt (A0A310TTQ1)
Pfam (PF00125)
UniProt (by SIFTS) (P02302)
Xenopus laevis (African clawed frog)
2B, F
(B, F)
Histone H4polymer10311394.42UniProt (P62799)
Pfam (PF15511)
Xenopus laevis (African clawed frog)
3C, G
(C, G)
Ubiquitin-60S ribosomal protein L40,Histone H2Apolymer22124045.42UniProt (P0CH09)
UniProt (Q6AZJ8)
Pfam (PF00240)
Pfam (PF00125)
Pfam (PF16211)
UniProt (by SIFTS) (P06897)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
4D, H
(D, H)
Histone H2B 1.1polymer12313655.92UniProt (P02281)
Pfam (PF00125)
Xenopus laevis (African clawed frog)H2B1.1
5I
(I)
DNA (149-MER)polymer14945764.11synthetic construct
6J
(J)
DNA (149-MER)polymer14946222.41synthetic construct
Sequence modifications
A, E: 0 - 135 (UniProt: A0A310TTQ1)
PDBExternal DatabaseDetails
Met 36Lys 37engineered mutation
C, G: -71 - 3 (UniProt: P0CH09)
PDBExternal DatabaseDetails
Met -91-initiating methionine
Asp -90-expression tag
Ser -89-expression tag
Pro -88-expression tag
Asp -87-expression tag
Leu -86-expression tag
His -85-expression tag
His -84-expression tag
His -83-expression tag
His -82-expression tag
His -81-expression tag
His -80-expression tag
Gly -79-expression tag
Thr -78-expression tag
Leu -77-expression tag
Val -76-expression tag
Pro -75-expression tag
Arg -74-expression tag
Gly -73-expression tag
Ser -72-expression tag
Thr 4-linker
Ser 5-linker
Ser 6-linker
Gly 7-linker
Gly 8-linker
Ser 9-linker
Gly 10-linker
Gly 11-linker
Ser 12-linker
Gly 13-linker
Gly 14-linker
Ser 15-linker
Gly 16-linker
C, G: 17 - 129 (UniProt: Q6AZJ8)
D, H: 1 - 122 (UniProt: P02281)
PDBExternal DatabaseDetails
Met 0-initiating methionine
Thr 29Ser 33engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight221052.5
All*Total formula weight221052.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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