6PWU
Structure of full-length, fully glycosylated, non-modified HIV-1 gp160 bound to PG16 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, C, E) | Envelope glycoprotein gp160 | polymer | 858 | 97560.7 | 3 | UniProt (Q71014) Pfam (PF00516) Pfam (PF00517) | Human immunodeficiency virus 1 | |
| 2 | D (H) | Antibody PG16 Fab heavy chain | polymer | 297 | 31952.7 | 1 | Homo sapiens (Human) | ||
| 3 | E (L) | Antibody PG16 Fab light chain | polymer | 250 | 26424.2 | 1 | Homo sapiens (Human) | ||
| 4 | F (B) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1114.0 | 1 | In PDB GlyTouCan (G08429SS) | |||
| 5 | G, H (D, F) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
| 6 | AA, BA, CA, DA, FA... (a, b, c, d, f...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 16 | In PDB GlyTouCan (G15407YE) | |||
| 7 | EA, IA, J, L, M... (e, i, I, K, M...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 10 | In PDB GlyTouCan (G42666HT) | |||
| 8 | Q (Q) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 9 | X (X) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G55220VL) | |||
| 10 | JA (j) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 11 | AB, AC, BB, BC, CB... (A, E, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 44 | Chemie (NAG) |
Sequence modifications
A, C, E: 31 - 1717 (UniProt: Q71014)
| PDB | External Database | Details |
|---|---|---|
| Met 2 | - | initiating methionine |
| Arg 3 | - | expression tag |
| Val 4 | - | expression tag |
| Arg 5 | - | expression tag |
| Gly 6 | - | expression tag |
| Ile 7 | - | expression tag |
| Gln 8 | - | expression tag |
| Arg 9 | - | expression tag |
| Asn 10 | - | expression tag |
| Cys 11 | - | expression tag |
| Gln 12 | - | expression tag |
| His 13 | - | expression tag |
| Leu 14 | - | expression tag |
| Trp 15 | - | expression tag |
| Arg 16 | - | expression tag |
| Trp 17 | - | expression tag |
| Gly 18 | - | expression tag |
| Thr 19 | - | expression tag |
| Leu 20 | - | expression tag |
| Ile 21 | - | expression tag |
| Leu 22 | - | expression tag |
| Gly 23 | - | expression tag |
| Met 24 | - | expression tag |
| Leu 25 | - | expression tag |
| Met 26 | - | expression tag |
| Ile 27 | - | expression tag |
| Cys 28 | - | expression tag |
| Ser 29 | - | expression tag |
| Ala 30 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 351059.0 | |
| Branched | Number of molecules | 32 |
| Total formula weight | 19102.7 | |
| Non-Polymers* | Number of molecules | 44 |
| Total formula weight | 9733.2 | |
| All* | Total formula weight | 379894.8 |
