6PW9
Cryo-EM structure of human NatE/HYPK complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | N-alpha-acetyltransferase 50 | polymer | 169 | 19427.4 | 1 | UniProt (Q9GZZ1) Pfam (PF00583) | Homo sapiens (Human) | hNaa50p,N-acetyltransferase 13,N-acetyltransferase 5,hNAT5,N-acetyltransferase san homolog,hSAN,N-epsilon-acetyltransferase 50,NatE catalytic subunit |
| 2 | B (B) | N-alpha-acetyltransferase 15, NatA auxiliary subunit | polymer | 866 | 101427.6 | 1 | UniProt (Q9BXJ9) Pfam (PF13181) Pfam (PF12569) | Homo sapiens (Human) | Gastric cancer antigen Ga19, N-terminal acetyltransferase, NMDA receptor-regulated protein 1, Protein tubedown-1, Tbdn100 |
| 3 | C (C) | N-alpha-acetyltransferase 10 | polymer | 236 | 26522.6 | 1 | UniProt (P41227) Pfam (PF00583) | Homo sapiens (Human) | N-terminal acetyltransferase complex ARD1 subunit homolog A,hARD1,NatA catalytic subunit Naa10 |
| 4 | D (D) | Huntingtin-interacting protein K | polymer | 129 | 14689.5 | 1 | UniProt (Q9NX55) Pfam (PF19026) | Homo sapiens (Human) | Huntingtin yeast partner K |
| 5 | E (C) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 1 | Chemie (IHP) | |||
| 6 | F (C) | ACETYL COENZYME *A | non-polymer | 809.6 | 1 | Chemie (ACO) |
Sequence modifications
C: 1 - 235 (UniProt: P41227)
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 162067.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1469.6 | |
| All* | Total formula weight | 163536.6 |
