6PVO

Cryo-EM structure of mouse TRPV3-Y564A in putative sensitized state at 37 degrees Celsius

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Transient receptor potential cation channel subfamily V member 3	polymer	808	92538.6	4	UniProt (Q8K424) Pfam (PF12796) Pfam (PF00023) Pfam (PF00520)	Mus musculus (Mouse)	TrpV3

Sequence modifications

A, B, C, D: 1 - 791 (UniProt: Q8K424)

PDB	External Database	Details
Ala 564	Tyr 564	engineered mutation
Leu 792	-	expression tag
Val 793	-	expression tag
Pro 794	-	expression tag
Arg 795	-	expression tag
Gly 796	-	expression tag
Ser 797	-	expression tag
Ala 798	-	expression tag
Ala 799	-	expression tag
Ala 800	-	expression tag
Trp 801	-	expression tag
Ser 802	-	expression tag
His 803	-	expression tag
Pro 804	-	expression tag
Gln 805	-	expression tag
Phe 806	-	expression tag
Glu 807	-	expression tag
Lys 808	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	370154.4
All*	Total formula weight	370154.4

*Water molecules are not included.