6PUS
Human TRPM2 bound to ADPR and calcium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, C, D, B) | Transient receptor potential cation channel subfamily M member 2 | polymer | 1512 | 172280.1 | 4 | UniProt (O94759) Pfam (PF18139) Pfam (PF00520) | Homo sapiens (Human) | TRPM2, Estrogen-responsive element-associated gene 1 protein, Long transient receptor potential channel 2, LTrpC2, Transient receptor potential channel 7, TrpC7, Transient receptor potential melastatin 2 |
| 2 | E, F, H, I, K... (A, C, D, B) | ADENOSINE-5-DIPHOSPHORIBOSE | non-polymer | 559.3 | 8 | Chemie (APR) | |||
| 3 | G, J, M, P (A, C, D, B) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) |
Sequence modifications
A, C, D, B: 1 - 1503 (UniProt: O94759)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Arg -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Thr 0 | - | expression tag |
| Phe 1504 | - | expression tag |
| Glu 1505 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 689120.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4634.8 | |
| All* | Total formula weight | 693755.1 |
