6PPJ

Cryo-EM structure of AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B	UvrD/REP helicase	polymer	1095	114735.9	1	UniProt (A0A0D6HIW1) Pfam (PF00580) Pfam (PF13361) Pfam (PF12705) UniProt (by SIFTS) (A0QTS0) In PDB	Mycobacterium smegmatis
2	A	ATP-dependent DNA helicase (UvrD/REP)	polymer	1045	110899.6	1	UniProt (A0A0D6HKQ2) Pfam (PF00580) Pfam (PF13361) Pfam (PF12705) UniProt (by SIFTS) (A0QTR9) In PDB	Mycobacterium smegmatis
3	A	IRON/SULFUR CLUSTER	non-polymer		351.6	1	Chemie (SF4)
4	A	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	1	Chemie (ANP)

Sequence modifications

B: 1 - 194 (UniProt: A0A0D6HIW1)
B: 195 - 221 (PDB: 6PPJ)
B: 222 - 355 (UniProt: A0A0D6HIW1)
B: 355 - 376 (PDB: 6PPJ)
B: 394 - 878 (UniProt: A0A0D6HIW1)

PDB	External Database	Details
Thr 537	Ser 537	conflict
Val 540	Leu 540	conflict
Glu 559	Gln 559	conflict
Ala 599	Val 599	conflict
Gly 627	Ser 627	conflict

B: 878 - 917 (PDB: 6PPJ)
B: 920 - 1062 (UniProt: A0A0D6HIW1)

PDB	External Database	Details
Ala 1014	Asp 1014	engineered mutation

B: 1063 - 1081 (PDB: 6PPJ)
B: 1082 - 1097 (PDB: 6PPJ)
A: 1 - 1045 (UniProt: A0A0D6HKQ2)

PDB	External Database	Details
Ala 934	Asp 934	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	225635.5
Non-Polymers*	Number of molecules	2
	Total formula weight	857.8
All*	Total formula weight	226493.3

*Water molecules are not included.