6POL

Crystal structure of the human NELL1 EGF1-3-Robo3 FN1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E	Roundabout homolog 3	polymer	114	12254.5	3	UniProt (Q96MS0) Pfam (PF00041) In PDB	Homo sapiens (Human)	Roundabout-like protein 3
2	B, D, F	Protein kinase C-binding protein NELL1	polymer	139	15297.9	3	UniProt (Q92832) Pfam (PF07645) Pfam (PF12947) In PDB	Homo sapiens (Human)	NEL-like protein 1,Nel-related protein 1
3	F, A, B, C, D...	NITRATE ION	non-polymer		62.0	14	Chemie (NO3)
4	B, D, F	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
5	B, D, F	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
6	B, D	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
7		water	water		18.0	642	Chemie (HOH)

Sequence modifications

A, C, E: 549 - 652 (UniProt: Q96MS0)

PDB	External Database	Details
Ala 547	-	expression tag
Asp 548	-	expression tag
Glu 653	-	expression tag
Phe 654	-	expression tag
His 655	-	expression tag
His 656	-	expression tag
His 657	-	expression tag
His 658	-	expression tag
His 659	-	expression tag
His 660	-	expression tag

B, D, F: 390 - 517 (UniProt: Q92832)

PDB	External Database	Details
Ala 387	-	expression tag
Asp 388	-	expression tag
Pro 389	-	expression tag
Glu 518	-	expression tag
Phe 519	-	expression tag
His 520	-	expression tag
His 521	-	expression tag
His 522	-	expression tag
His 523	-	expression tag
His 524	-	expression tag
His 525	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	82656.9
Non-Polymers*	Number of molecules	22
	Total formula weight	1836.1
All*	Total formula weight	84493.1

*Water molecules are not included.