6PLV

CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in nanodisc, closed state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E	Glycine receptor subunit alphaZ1	polymer	458	52537.6	5	UniProt (O93430) Pfam (PF02931) Pfam (PF02932) In PDB	Danio rerio (Zebrafish)
2	F, G, H, I, J	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	5	In PDB GlyTouCan (G42666HT)
3	B, D, A, C, E	UNKNOWN LIGAND	non-polymer		142.3	60	Chemie (UNL)
4	B, D, E, A, C	GAMMA-AMINO-BUTANOIC ACID	non-polymer		103.1	5	Chemie (ABU)

Sequence modifications

A, B, C, D, E: -7 - 436 (UniProt: O93430)

PDB	External Database	Details
Leu 437	-	expression tag
Val 438	-	expression tag
Pro 439	-	expression tag
Arg 440	-	expression tag
Gly 441	-	expression tag
Ser 442	-	expression tag
His 443	-	expression tag
His 444	-	expression tag
His 445	-	expression tag
His 446	-	expression tag
His 447	-	expression tag
His 448	-	expression tag
His 449	-	expression tag
His 450	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	262688.0
Branched	Number of molecules	5
	Total formula weight	2122.0
Non-Polymers*	Number of molecules	65
	Total formula weight	9052.5
All*	Total formula weight	273862.5

*Water molecules are not included.