6PLE

Crystal structure of MhuD R26S mutant in complex with biliverdin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Heme oxygenase (mycobilin-producing)	polymer	123	13122.8	2	UniProt (P9WKH3) Pfam (PF03992)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	Mycobacterial heme utilization,degrader,MHUD
2	C, D, E, F, G (A, B)	BILIVERDINE IX ALPHA	non-polymer		582.6	5	Chemie (BLA)
3	H, I (A, B)	water	water		18.0	16	Chemie (HOH)

Sequence modifications

A, B: 1 - 105 (UniProt: P9WKH3)

PDB	External Database	Details
Ser 26	Arg 26	engineered mutation
Gly 106	-	expression tag
Val 107	-	expression tag
Pro 108	-	expression tag
Arg 109	-	expression tag
Gly 110	-	expression tag
Lys 111	-	expression tag
Leu 112	-	expression tag
Ala 113	-	expression tag
Ala 114	-	expression tag
Ala 115	-	expression tag
Leu 116	-	expression tag
Glu 117	-	expression tag
His 118	-	expression tag
His 119	-	expression tag
His 120	-	expression tag
His 121	-	expression tag
His 122	-	expression tag
His 123	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	26245.5
Non-Polymers*	Number of molecules	5
	Total formula weight	2913.2
All*	Total formula weight	29158.8

*Water molecules are not included.