6PKY

Guinea pig N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA) catalytic domain auto-inhibited by pro-peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA)	polymer	312	33908.8	4	UniProt (H0VTT5) Pfam (PF09992)	Cavia porcellus (Guinea pig)
2	E (E)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
3	F, W (A, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
4	FA, G, P, X (D, A, B, C)	BROMIDE ION	non-polymer		79.9	4	Chemie (BR)
5	AA, BA, CA, DA, EA... (C, D, A, B)	CHLORIDE ION	non-polymer		35.5	32	Chemie (CL)
6	RA, SA, TA, UA (A, B, C, D)	water	water		18.0	119	Chemie (HOH)

Sequence modifications

A, B, C, D: 26 - 327 (UniProt: H0VTT5)

PDB	External Database	Details
Asp 16	-	expression tag
Arg 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
His 20	-	expression tag
His 21	-	expression tag
His 22	-	expression tag
His 23	-	expression tag
Lys 24	-	expression tag
Leu 25	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	135635.4
Branched	Number of molecules	1
	Total formula weight	570.5
Non-Polymers*	Number of molecules	38
	Total formula weight	1896.5
All*	Total formula weight	138102.4

*Water molecules are not included.