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6PJC

HIV-1 Protease NL4-3 WT in Complex with LR4-41

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(B, A, D, C)
Protease NL4-3polymer9910831.84UniProt (Q8ULI9)
Pfam (PF00077)
UniProt (by SIFTS) (P12497)
Human immunodeficiency virus 1
2E, F, H, I
(B, A, D)
SULFATE IONnon-polymer96.14Chemie (SO4)
3G, J
(A, C)
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,4S,5S)-5-{[(2,6-dimethylphenoxy)acetyl]amino}-4-hydroxy-1,6-diphenylhexan-2-yl]carbamatenon-polymer602.72Chemie (OR1)
4K, L, M, N
(B, A, D, C)
waterwater18.073Chemie (HOH)
Sequence modifications
B, A, D, C: 1 - 99 (UniProt: Q8ULI9)
PDBExternal DatabaseDetails
Lys 7Gln 7engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight43327.3
Non-Polymers*Number of molecules6
Total formula weight1589.7
All*Total formula weight44917.0
*Water molecules are not included.

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PDB entries from 2025-07-30

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