6PHS
Protein Tyrosine Phosphatase 1B (1-301), P185A mutant, vanadate bound state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase non-receptor type 1 | polymer | 297 | 34563.3 | 1 | UniProt (P18031) Pfam (PF00102) | Homo sapiens (Human) | Protein-tyrosine phosphatase 1B,PTP-1B |
| 2 | B (A) | VANADATE ION | non-polymer | 114.9 | 1 | Chemie (VO4) | |||
| 3 | C, D (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | E (A) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A: 2 - 298 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Ala 185 | Pro 185 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34563.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 299.1 | |
| All* | Total formula weight | 34862.5 |
