6PHF

Pfs25 in complex with the human transmission blocking antibody 2587

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, C)	2587 Antibody Fab, Heavy Chain	polymer	223	23951.7	2		Homo sapiens (Human)
2	B, E (G, E)	25 kDa ookinete surface antigen	polymer	184	20233.3	2	UniProt (P13829) Pfam (PF06247)	Plasmodium falciparum	Pfs25
3	C, F (B, D)	2587 Antibody Fab, Light Chain	polymer	213	22776.1	2		Homo sapiens (Human)

Sequence modifications

G, E: 1 - 172 (UniProt: P13829)

PDB	External Database	Details
Glu -2	-	expression tag
Thr -1	-	expression tag
Gly 0	-	expression tag
Gln 91	Asn 112	conflict
Gln 144	Asn 165	conflict
Gln 166	Asn 187	conflict
Gly 173	-	expression tag
Thr 174	-	expression tag
Lys 175	-	expression tag
His 176	-	expression tag
His 177	-	expression tag
His 178	-	expression tag
His 179	-	expression tag
His 180	-	expression tag
His 181	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	133922.3
All*	Total formula weight	133922.3

*Water molecules are not included.