6PGQ
Crystal structure of N-glycosylated human calcitonin receptor extracellular domain in complex with salmon calcitonin (22-32)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Maltodextrin-binding protein,Calcitonin receptor | polymer | 482 | 54078.9 | 1 | UniProt (A0A0A8UN35) UniProt (P30988) Pfam (PF02793) In PDB | Escherichia coli | CT-R |
2 | B | Calcitonin | polymer | 12 | 1149.2 | 1 | UniProt (Q92163) UniProt (by SIFTS) (P01263) In PDB | Oncorhynchus sp. | |
3 | C | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | alpha-maltose | ||
4 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
5 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
6 | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A: -333 - 33 (UniProt: A0A0A8UN35)
A: 39 - 141 (UniProt: P30988)
B: 22 - 32 (UniProt: Q92163)
PDB | External Database | Details |
---|---|---|
Met -334 | - | initiating methionine |
Asn 34 | - | linker |
Ala 35 | - | linker |
Ala 36 | - | linker |
Ala 37 | - | linker |
Glu 38 | - | linker |
PDB | External Database | Details |
---|---|---|
His 142 | - | expression tag |
His 143 | - | expression tag |
His 144 | - | expression tag |
His 145 | - | expression tag |
His 146 | - | expression tag |
His 147 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Nh2 33 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 55228.1 | |
Branched | Number of molecules | 1 |
Total formula weight | 342.3 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 722.7 | |
All* | Total formula weight | 56293.1 |