6PGQ

Crystal structure of N-glycosylated human calcitonin receptor extracellular domain in complex with salmon calcitonin (22-32)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Maltodextrin-binding protein,Calcitonin receptor	polymer	482	54078.9	1	UniProt (A0A0A8UN35) UniProt (P30988) Pfam (PF02793) In PDB	Escherichia coli	CT-R
2	B	Calcitonin	polymer	12	1149.2	1	UniProt (Q92163) UniProt (by SIFTS) (P01263) In PDB	Oncorhynchus sp.
3	C	alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose	branched		342.3	1	In PDB BIRD (PRD_900001) GlyTouCan (G07411ON)		alpha-maltose
4	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
5	A	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
6		water	water		18.0	2	Chemie (HOH)

Sequence modifications

A: -333 - 33 (UniProt: A0A0A8UN35)

PDB	External Database	Details
Met -334	-	initiating methionine
Asn 34	-	linker
Ala 35	-	linker
Ala 36	-	linker
Ala 37	-	linker
Glu 38	-	linker

A: 39 - 141 (UniProt: P30988)

PDB	External Database	Details
His 142	-	expression tag
His 143	-	expression tag
His 144	-	expression tag
His 145	-	expression tag
His 146	-	expression tag
His 147	-	expression tag

B: 22 - 32 (UniProt: Q92163)

PDB	External Database	Details
Nh2 33	-	amidation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	55228.1
Branched	Number of molecules	1
	Total formula weight	342.3
Non-Polymers*	Number of molecules	4
	Total formula weight	722.7
All*	Total formula weight	56293.1

*Water molecules are not included.