6PEY

MTHFR with mutation Asp120Ala

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Methylenetetrahydrofolate reductase	polymer	304	34171.8	3	UniProt (C3SIT0) Pfam (PF02219) UniProt (by SIFTS) (P0AEZ1) In PDB	Escherichia coli
2	A, B, C	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	3	Chemie (FAD)
3		water	water		18.0	3	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 296 (UniProt: C3SIT0)

PDB	External Database	Details
Ala 120	Asp 120	engineered mutation
Leu 297	-	expression tag
Glu 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	102515.5
Non-Polymers*	Number of molecules	3
	Total formula weight	2356.6
All*	Total formula weight	104872.2

*Water molecules are not included.