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6PDZ

Crystal structure of PPARgamma ligand binding domain in complex with SMRT peptide and inverse agonist T0070907

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(B, A)
Peroxisome proliferator-activated receptor gammapolymer27531449.52UniProt (P37231)
Pfam (PF00104)
Homo sapiens (Human)PPAR-gamma,Nuclear receptor subfamily 1 group C member 3
2B, D
(C, D)
Nuclear receptor corepressor 2polymer222600.02UniProt (Q9Y618)Homo sapiens (Human)N-CoR2,CTG repeat protein 26,SMAP270,Silencing mediator of retinoic acid and thyroid hormone receptor,SMRT,T3 receptor-associating factor,TRAC,Thyroid-,retinoic-acid-receptor-associated corepressor
3E, F
(B, A)
2-chloro-5-nitro-N-(pyridin-4-yl)benzamidenon-polymer277.72Chemie (EEY)
4G, H, I, J
(B, C, A, D)
waterwater18.0532Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight68099.0
Non-Polymers*Number of molecules2
Total formula weight555.3
All*Total formula weight68654.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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