6PDZ
Crystal structure of PPARgamma ligand binding domain in complex with SMRT peptide and inverse agonist T0070907
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C (B, A) | Peroxisome proliferator-activated receptor gamma | polymer | 275 | 31449.5 | 2 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
2 | B, D (C, D) | Nuclear receptor corepressor 2 | polymer | 22 | 2600.0 | 2 | UniProt (Q9Y618) | Homo sapiens (Human) | N-CoR2,CTG repeat protein 26,SMAP270,Silencing mediator of retinoic acid and thyroid hormone receptor,SMRT,T3 receptor-associating factor,TRAC,Thyroid-,retinoic-acid-receptor-associated corepressor |
3 | E, F (B, A) | 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide | non-polymer | 277.7 | 2 | Chemie (EEY) | |||
4 | G, H, I, J (B, C, A, D) | water | water | 18.0 | 532 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 68099.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 555.3 | |
All* | Total formula weight | 68654.4 |