6PCI
EBOV GPdMuc (Makona) in complex with rEBOV-520 and rEBOV-548 Fabs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, G, M (A, B, C) | Virion spike glycoprotein | polymer | 278 | 31096.9 | 3 | UniProt (A0A1C4HDV6) Pfam (PF01611) UniProt (by SIFTS) (A0A068J419) | Ebola virus | |
| 2 | B, H, N (H, I, J) | rEBOV-548 Fab heavy chain | polymer | 234 | 25223.4 | 3 | Homo sapiens | ||
| 3 | C, I, O (K, L, M) | rEBOV-548 Fab light chain | polymer | 214 | 23324.8 | 3 | Homo sapiens | ||
| 4 | D, J, P (D, E, F) | Virion spike glycoprotein,Virion spike glycoprotein,Ebola Virus (Makona) GP2 | polymer | 203 | 22142.6 | 3 | UniProt (A0A0F6PDW0) Pfam (PF22307) UniProt (by SIFTS) (A0A068J419) | Zaire ebolavirus | |
| 5 | E, K, Q (Q, R, S) | rEBOV-520 Fab light chain | polymer | 215 | 23434.9 | 3 | Homo sapiens | ||
| 6 | F, L, R (N, O, P) | rEBOV-520 Fab heavy chain | polymer | 227 | 24074.0 | 3 | Homo sapiens | ||
| 7 | S, T, U (G, T, U) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 8 | AA, BA, CA, DA, EA... (B, C, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) |
Sequence modifications
D, E, F: 461 - 629 (UniProt: A0A0F6PDW0)
D, E, F: 630 - 663 (PDB: 6PCI)
| PDB | External Database | Details |
|---|---|---|
| Phe 517 | Tyr 517 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 447889.7 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 2732.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2654.5 | |
| All* | Total formula weight | 453276.7 |
