6PC3

Crystal structure of Helicobacter pylori PPX/GppA in complex with GSP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Guanosine pentaphosphate phosphohydrolase	polymer	495	55655.5	2	UniProt (B5ZA44) Pfam (PF02541) Pfam (PF21447)	Helicobacter pylori (strain G27)
2	C, L (A, B)	5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE	non-polymer		539.2	2	Chemie (GSP)
3	D, M (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	E, F, N, O (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
5	G, P (A, B)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
6	H, I, Q (A, B)	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
7	J (A)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
8	K, R (A, B)	Monothiophosphate	non-polymer		114.1	2	Chemie (TS6)
9	S, T (A, B)	water	water		18.0	438	Chemie (HOH)

Sequence modifications

A, B: 2 - 484 (UniProt: B5ZA44)

PDB	External Database	Details
Met -10	-	initiating methionine
Arg -9	-	expression tag
Gly -8	-	expression tag
Ser -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
Gly 0	-	expression tag
Ser 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	111311.1
Non-Polymers*	Number of molecules	16
	Total formula weight	1840.4
All*	Total formula weight	113151.5

*Water molecules are not included.