6P8C
2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase (MthRED) from Methanothermobacter thermautotrophicus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase | polymer | 249 | 27397.4 | 2 | UniProt (O26337) Pfam (PF01872) In PDB | Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) | DARP reductase,2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one reductase,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthase,DARIPP synthase |
| 2 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | A, B | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 6 | water | water | 18.0 | 266 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 216 (UniProt: O26337)
| PDB | External Database | Details |
|---|---|---|
| Met -32 | - | initiating methionine |
| His -31 | - | expression tag |
| His -30 | - | expression tag |
| His -29 | - | expression tag |
| His -28 | - | expression tag |
| His -27 | - | expression tag |
| His -26 | - | expression tag |
| Gly -25 | - | expression tag |
| Lys -24 | - | expression tag |
| Pro -23 | - | expression tag |
| Ile -22 | - | expression tag |
| Pro -21 | - | expression tag |
| Asn -20 | - | expression tag |
| Pro -19 | - | expression tag |
| Leu -18 | - | expression tag |
| Leu -17 | - | expression tag |
| Gly -16 | - | expression tag |
| Leu -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Ser -13 | - | expression tag |
| Thr -12 | - | expression tag |
| Glu -11 | - | expression tag |
| Asn -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Tyr -8 | - | expression tag |
| Phe -7 | - | expression tag |
| Gln -6 | - | expression tag |
| Gly -5 | - | expression tag |
| Ile -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Phe -1 | - | expression tag |
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54794.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1950.4 | |
| All* | Total formula weight | 56745.2 |
