6P6W
Cryo-EM structure of voltage-gated sodium channel NavAb N49K/L109A/M116V/G94C/Q150C disulfide crosslinked mutant in the resting state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Fusion of Maltose-binding protein and voltage-gated sodium channel NavAb | polymer | 661 | 74072.8 | 4 | UniProt (A0A028ANC5) UniProt (A8EVM5) Pfam (PF01547) Pfam (PF00520) Pfam (PF08016) UniProt (by SIFTS) (P0AEX9) In PDB | Escherichia coli K-12 | dihydrodipicolinate synthase |
Sequence modifications
A, B, C, D: 607 - 998 (UniProt: A0A028ANC5)
A, B, C, D: 1001 - 1267 (UniProt: A8EVM5)
PDB | External Database | Details |
---|---|---|
Asn 999 | - | linker |
Ala 1000 | - | linker |
PDB | External Database | Details |
---|---|---|
Ala 1004 | Arg 4 | engineered mutation |
Lys 1049 | Asn 49 | engineered mutation |
Cys 1094 | Gly 94 | engineered mutation |
Ala 1109 | Leu 109 | engineered mutation |
Val 1116 | Met 116 | engineered mutation |
Cys 1150 | Gln 150 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 296291.2 | |
All* | Total formula weight | 296291.2 |