6P64
Alpha-beta TCR Binding to Neoantigen KQWLVWLFL Presented by HLA-A206
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, F) | MHC class I antigen | polymer | 276 | 32001.4 | 2 | UniProt (U5YJP1) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (Q53Z42) | Homo sapiens (Human) | HLA-A*02:06 |
| 2 | B, D (B, G) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | E, G (D, I) | 302TIL TCR alpha chain | polymer | 208 | 23541.1 | 2 | Homo sapiens (Human) | ||
| 4 | F, H (E, J) | 302TIL TCR beta chain | polymer | 245 | 27783.0 | 2 | Homo sapiens (Human) | ||
| 5 | I, J (C, H) | Neoantigen peptide KQWLVWLFL | polymer | 9 | 1233.5 | 2 | UniProt (by SIFTS) (Q5VTY9) | Homo sapiens | |
| 6 | K, L, M, N, O (A, B, F, I) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 7 | P, Q, R, S, T... (A, B, F, D, E...) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A, F: 1 - 275 (UniProt: U5YJP1)
B, G: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 192876.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 460.5 | |
| All* | Total formula weight | 193337.3 |
