6P3R
crystal structure of human Fab H5.31 in complex with influenza A H5N1 Vietnam hemagglutinin head domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | human Fab H5.31 heavy chain | polymer | 230 | 24659.7 | 2 | Homo sapiens | ||
| 2 | B, D (B, D) | Human Fab H5.31 light chain | polymer | 215 | 23396.0 | 2 | Homo sapiens | ||
| 3 | E, F (E, L) | Hemagglutinin | polymer | 219 | 25162.4 | 2 | UniProt (Q1KHK2) Pfam (PF00509) | Influenza A virus (A/chicken/Vietnam/32/2004(H5N1)) | |
| 4 | G (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | ||||
| 5 | H (G) | N-acetyl-alpha-neuraminic acid-(2-6)-alpha-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1567.4 | 1 | ||||
| 6 | I (H) | N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-D-fructofuranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1567.4 | 1 | ||||
| 7 | J, L, N (B, D, L) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 8 | K, M, O (C, E, L) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 9 | P, Q, R, S, T (A, B, C, D, L) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
E, L: 58 - 268 (UniProt: Q1KHK2)
| PDB | External Database | Details |
|---|---|---|
| Ala 269 | - | expression tag |
| Ala 270 | - | expression tag |
| His 271 | - | expression tag |
| His 272 | - | expression tag |
| His 273 | - | expression tag |
| His 274 | - | expression tag |
| His 275 | - | expression tag |
| His 276 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 146436.2 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 3559.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 948.5 | |
| All* | Total formula weight | 150943.9 |
