6P2F
Structure of a nested set of N-terminally extended MHC I-peptides provides novel insights into antigen processing and presentation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | HLA class I histocompatibility antigen, B-8 alpha chain | polymer | 276 | 31902.0 | 1 | UniProt (P30460) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P01889) In PDB | Homo sapiens (Human) | MHC class I antigen B*8 |
| 2 | B | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
| 3 | C | MHC I-peptide | polymer | 14 | 1553.9 | 1 | Human immunodeficiency virus 1 | ||
| 4 | water | water | 18.0 | 274 | Chemie (HOH) |
Sequence modifications
A: 1 - 276 (UniProt: P30460)
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Cys 76 | Glu 100 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 45335.3 | |
| All* | Total formula weight | 45335.3 |
