6P27
Structure of a nested set of N-terminally extended MHC I-peptides provides novel insights into antigen processing and presentation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, B-8 alpha chain | polymer | 276 | 31902.0 | 1 | UniProt (P30460) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P01889) | Homo sapiens (Human) | MHC class I antigen B*8 |
| 2 | B (B) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C (C) | MHC I-peptide | polymer | 12 | 1397.8 | 1 | Human immunodeficiency virus 1 | ||
| 4 | D, E, F (A, B, C) | water | water | 18.0 | 236 | Chemie (HOH) |
Sequence modifications
A: 1 - 276 (UniProt: P30460)
| PDB | External Database | Details |
|---|---|---|
| Cys 76 | Glu 100 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 45047.9 | |
| All* | Total formula weight | 45047.9 |
