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6P1M

Binary complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA-directed DNA/RNA polymerase mupolymer35439844.21UniProt (Q9NP87)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
In PDB
Homo sapiens (Human)Pol Mu,Terminal transferase
2TDNA (5'-D(*CP*GP*GP*CP*(8OG)P*TP*AP*CP*G)-3')polymer92772.81Homo sapiens
3PDNA (5'-D(*CP*GP*TP*A)-3')polymer41190.81Homo sapiens
4DDNA (5'-D(P*GP*CP*CP*G)-3')polymer41191.81Homo sapiens
5ABROMIDE IONnon-polymer79.92Chemie (BR)
6APOTASSIUM IONnon-polymer39.11Chemie (K)
7ACHLORIDE IONnon-polymer35.52Chemie (CL)
8ACARBON DIOXIDEnon-polymer44.01Chemie (CO2)
9A1,2-ETHANEDIOLnon-polymer62.16Chemie (EDO)
10waterwater18.0390Chemie (HOH)
Sequence modifications
A: 134 - 494 (UniProt: Q9NP87)
PDBExternal DatabaseDetails
Gly 129-expression tag
Ser 130-expression tag
Ala 131-expression tag
Ala 132-expression tag
Ala 133-expression tag
-Pro 398deletion
-Gly 399deletion
-Ala 400deletion
-Ala 401deletion
-Val 402deletion
-Gly 403deletion
-Gly 404deletion
-Ser 405deletion
-Thr 406deletion
-Arg 407deletion
-Pro 408deletion
-Cys 409deletion
Gly 410Pro 410linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight44999.6
Non-Polymers*Number of molecules12
Total formula weight686.2
All*Total formula weight45685.8
*Water molecules are not included.

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PDB entries from 2024-09-11

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