6P12
Structure of spastin AAA domain (wild-type) in complex with diaminotriazole-based inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B | Drosophila melanogaster Spastin AAA domain | polymer | 313 | 34191.8 | 1 | UniProt (Q8I0P1) Pfam (PF00004) Pfam (PF17862) Pfam (PF09336) In PDB | Drosophila melanogaster (Fruit fly) | D-Spastin,Dm-Spastin,Dspastin |
| 2 | B | 3-{[5-amino-1-(2-fluoro-6-methoxybenzene-1-carbonyl)-1H-1,2,4-triazol-3-yl]amino}-N-methylbenzamide | non-polymer | 384.4 | 1 | Chemie (NKY) | |||
| 3 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | B | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 5 | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34191.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 598.6 | |
| All* | Total formula weight | 34790.4 |
