6P0A
Human DNA Ligase 1 Bound to an Adenylated, dideoxy Terminated DNA nick with 2 mM Mg2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA ligase 1 | polymer | 645 | 71786.0 | 1 | UniProt (P18858) Pfam (PF04675) Pfam (PF01068) Pfam (PF04679) In PDB | Homo sapiens (Human) | DNA ligase I,Polydeoxyribonucleotide synthase [ATP] 1 |
| 2 | B | DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3') | polymer | 11 | 3365.2 | 1 | synthetic construct | ||
| 3 | C | DNA (5'-D(P*GP*TP*CP*GP*GP*AP*C)-3') | polymer | 7 | 2138.4 | 1 | synthetic construct | ||
| 4 | D | DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3') | polymer | 18 | 5486.6 | 1 | synthetic construct | ||
| 5 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | C | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
| 7 | water | water | 18.0 | 663 | Chemie (HOH) |
Sequence modifications
A: 262 - 904 (UniProt: P18858)
| PDB | External Database | Details |
|---|---|---|
| Ser 260 | - | expression tag |
| Asn 261 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 82776.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 371.5 | |
| All* | Total formula weight | 83147.7 |
