6P06
Ternary structure of the E52D mutant of ANT-4 with Neomycin and AMPCPP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Kanamycin nucleotidyltransferase | polymer | 256 | 29121.9 | 2 | UniProt (P05058) Pfam (PF07827) UniProt (by SIFTS) (P05057) | Bacillus sp. | |
| 2 | C, G (A) | NEOMYCIN | non-polymer | 614.6 | 2 | Chemie (NMY) | |||
| 3 | D, I (A, B) | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | non-polymer | 505.2 | 2 | Chemie (APC) | |||
| 4 | E, F, H, J (A, B) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 199 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 253 (UniProt: P05058)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Asp 52 | Glu 52 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58243.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2400.0 | |
| All* | Total formula weight | 60643.7 |
