6P00

RebH Variant 8F, Tryptamine 6-halogenase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Flavin-dependent tryptophan halogenase RebH	polymer	550	62573.3	2	UniProt (Q8KHZ8) Pfam (PF04820)	Lechevalieria aerocolonigenes (Nocardia aerocolonigenes)	Variant of Flavin-dependent tryptophan halogenase RebH, 8F
2	C, D (A, B)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	2	Chemie (FAD)
3	E, F (A, B)	water	water		18.0	589	Chemie (HOH)

Sequence modifications

A, B: 1 - 530 (UniProt: Q8KHZ8)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Met 52	Ile 52	engineered mutation
Pro 110	Ser 110	engineered mutation
Leu 130	Ser 130	engineered mutation
Ser 166	Asn 166	engineered mutation
Phe 380	Leu 380	engineered mutation
Pro 448	Ser 448	engineered mutation
Trp 455	Tyr 455	engineered mutation
Leu 465	Phe 465	engineered mutation
Ser 470	Asn 470	engineered mutation
Arg 494	Gln 494	engineered mutation
Gln 509	Arg 509	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	125146.5
Non-Polymers*	Number of molecules	2
	Total formula weight	1571.1
All*	Total formula weight	126717.6

*Water molecules are not included.