6OZE
Crystal structure of the catalytic domain of human Endonuclease V (C140S/C225S/C226A/C228S)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Endonuclease V | polymer | 246 | 27157.4 | 1 | UniProt (Q8N8Q3) Pfam (PF04493) | Homo sapiens (Human) | hEndoV,Inosine-specific endoribonuclease |
| 2 | B, C (A) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 3 | D, E (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | F, G (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | H (A) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A: 9 - 254 (UniProt: Q8N8Q3)
| PDB | External Database | Details |
|---|---|---|
| Ala 57 | Lys 57 | conflict |
| Ser 140 | Cys 140 | engineered mutation |
| Ala 164 | Glu 164 | conflict |
| Ser 225 | Cys 225 | engineered mutation |
| Ala 226 | Cys 226 | engineered mutation |
| Ser 228 | Cys 228 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27157.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 348.3 | |
| All* | Total formula weight | 27505.6 |
