6OZ3
Crystal structure of broadly neutralizing antibody N49P9.1 Fab in complex with HIV-1 Clade A/E strain 93TH057 gp120 core
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | clade A/E 93TH057 HIV-1 gp120 core | polymer | 355 | 39356.6 | 1 | UniProt (A0A0M3KKW9) Pfam (PF00516) | Human immunodeficiency virus 1 | |
| 2 | B (H) | N49P9.1 antibody Fab heavy chain | polymer | 221 | 24081.2 | 1 | Homo sapiens (Human) | ||
| 3 | C (L) | N49P9.1 antibody Fab light chain | polymer | 203 | 21780.2 | 1 | Homo sapiens (Human) | ||
| 4 | D, E, F, G, H... (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 11 | Chemie (NAG) | |||
| 5 | O (H) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) |
Sequence modifications
G: 44 - 492 (UniProt: A0A0M3KKW9)
| PDB | External Database | Details |
|---|---|---|
| Val 42 | - | expression tag |
| Pro 43 | - | expression tag |
| Ser 375 | His 242 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 85218.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2456.3 | |
| All* | Total formula weight | 87674.3 |
