6OXL
CRYO-EM STRUCTURE OF PHOSPHORYLATED AP-2 (mu E302K) BOUND TO NECAP IN THE PRESENCE OF SS DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | AP-2 complex subunit alpha-2 | polymer | 621 | 69656.3 | 1 | Pfam (PF01602) UniProt (by SIFTS) (P17427) | Mus musculus (Mouse) | |
| 2 | B (B) | AP-2 complex subunit beta | polymer | 591 | 66953.2 | 1 | UniProt (Q9DBG3) Pfam (PF01602) | Mus musculus (Mouse) | AP105B,Adaptor protein complex AP-2 subunit beta,Adaptor-related protein complex 2 subunit beta,Beta-2-adaptin,Beta-adaptin,Clathrin assembly protein complex 2 beta large chain,Plasma membrane adaptor HA2/AP2 adaptin beta subunit |
| 3 | C (M) | AP-2 complex subunit mu | polymer | 435 | 49806.7 | 1 | UniProt (P84091) Pfam (PF01217) Pfam (PF00928) | Mus musculus (Mouse) | AP-2 mu chain,Adaptor protein complex AP-2 subunit mu,Adaptor-related protein complex 2 subunit mu,Clathrin assembly protein complex 2 mu medium chain,Clathrin coat assembly protein AP50,Clathrin coat-associated protein AP50,Mu2-adaptin,Plasma membrane adaptor AP-2 50 kDa protein |
| 4 | D (S) | AP-2 complex subunit sigma | polymer | 142 | 17038.7 | 1 | UniProt (P62744) Pfam (PF01217) | Rattus norvegicus (Rat) | Adaptor protein complex AP-2 subunit sigma,Adaptor-related protein complex 2 subunit sigma,Clathrin assembly protein 2 sigma small chain,Clathrin coat assembly protein AP17,Clathrin coat-associated protein AP17,Plasma membrane adaptor AP-2 17 kDa protein,Sigma-adaptin 3b,Sigma2-adaptin |
| 5 | E (N) | Adaptin ear-binding coat-associated protein 2 | polymer | 266 | 28629.9 | 1 | UniProt (Q9D1J1) Pfam (PF07933) | Mus musculus (Mouse) | NECAP endocytosis-associated protein 2,NECAP-2 |
| 6 | F (n) | Unknown region of Adaptin ear-binding coat-associated protein 2 Ex-domain | polymer | 7 | 613.7 | 1 | Mus musculus |
Sequence modifications
M: 1 - 435 (UniProt: P84091)
| PDB | External Database | Details |
|---|---|---|
| Lys 302 | Glu 302 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 232698.6 | |
| All* | Total formula weight | 232698.6 |
