6OVC
hMcl1 inhibitor complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 164 | 18866.4 | 1 | UniProt (Q07820) Pfam (PF00452) | Homo sapiens (Human) | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | B (A) | (2S)-N-(benzylsulfonyl)-4-(cyclobutylmethyl)-2-(2,4-dichlorophenyl)-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide | non-polymer | 545.5 | 1 | Chemie (N8J) |
Sequence modifications
A: 2 - 158 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ser 117 | Cys 286 | conflict |
| His 159 | - | expression tag |
| His 160 | - | expression tag |
| His 161 | - | expression tag |
| His 162 | - | expression tag |
| His 163 | - | expression tag |
| His 164 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18866.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 545.5 | |
| All* | Total formula weight | 19411.8 |
