6OU1
Crystal Structure of the Computationally-derived 21-Variant of the Myocilin Olfactomedin Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Myocilin | polymer | 277 | 31354.1 | 2 | UniProt (Q99972) Pfam (PF02191) In PDB | Homo sapiens (Human) | Myocilin 55 kDa subunit,Trabecular meshwork-induced glucocorticoid response protein |
| 2 | A, B | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 3 | A, B | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 289 | Chemie (HOH) |
Sequence modifications
A, B: 228 - 504 (UniProt: Q99972)
| PDB | External Database | Details |
|---|---|---|
| Val 255 | Leu 255 | conflict |
| Val 277 | Thr 277 | conflict |
| Asn 331 | Ser 331 | conflict |
| Gly 340 | Glu 340 | conflict |
| Asp 348 | Glu 348 | conflict |
| Lys 350 | Asn 350 | conflict |
| Tyr 369 | Phe 369 | conflict |
| Asn 386 | Ala 386 | conflict |
| Asn 395 | Asp 395 | conflict |
| Gln 396 | Glu 396 | conflict |
| Asn 400 | Ala 400 | conflict |
| Thr 410 | Asn 410 | conflict |
| Val 413 | Leu 413 | conflict |
| Asn 456 | Gly 456 | conflict |
| Thr 459 | Ile 459 | conflict |
| Tyr 462 | Thr 462 | conflict |
| Asp 464 | Thr 464 | conflict |
| Asn 474 | Ser 474 | conflict |
| Arg 484 | Lys 484 | conflict |
| Gly 492 | Leu 492 | conflict |
| His 493 | Asn 493 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62708.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 310.3 | |
| All* | Total formula weight | 63018.5 |
