6OTE

Crystal Structure of Seryl-tRNA synthetase (SerRS) from Cryptosporidium parvum complexed with L-Serylsulfamoyl Adenosine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Seryl-tRNA synthetase, cytoplasmic	polymer	572	65627.5	1	UniProt (Q5CVB3) Pfam (PF02403) Pfam (PF00587)	Cryptosporidium parvum (strain Iowa II)
2	B (A)	5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE	non-polymer		433.4	1	Chemie (SSA)
3	C (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	D (A)	water	water		18.0	11	Chemie (HOH)

Sequence modifications

A: 1 - 454 (UniProt: Q5CVB3)

PDB	External Database	Details
Met -117	-	initiating methionine
Ala -116	-	expression tag
His -115	-	expression tag
His -114	-	expression tag
His -113	-	expression tag
His -112	-	expression tag
His -111	-	expression tag
His -110	-	expression tag
Met -109	-	expression tag
Lys -108	-	expression tag
Ser -107	-	expression tag
Asp -106	-	expression tag
Ser -105	-	expression tag
Glu -104	-	expression tag
Val -103	-	expression tag
Asn -102	-	expression tag
Gln -101	-	expression tag
Glu -100	-	expression tag
Ala -99	-	expression tag
Lys -98	-	expression tag
Pro -97	-	expression tag
Glu -96	-	expression tag
Val -95	-	expression tag
Lys -94	-	expression tag
Pro -93	-	expression tag
Glu -92	-	expression tag
Val -91	-	expression tag
Lys -90	-	expression tag
Pro -89	-	expression tag
Glu -88	-	expression tag
Thr -87	-	expression tag
His -86	-	expression tag
Ile -85	-	expression tag
Asn -84	-	expression tag
Leu -83	-	expression tag
Lys -82	-	expression tag
Val -81	-	expression tag
Ser -80	-	expression tag
Asp -79	-	expression tag
Gly -78	-	expression tag
Ser -77	-	expression tag
Ser -76	-	expression tag
Glu -75	-	expression tag
Ile -74	-	expression tag
Phe -73	-	expression tag
Phe -72	-	expression tag
Lys -71	-	expression tag
Ile -70	-	expression tag
Lys -69	-	expression tag
Lys -68	-	expression tag
Thr -67	-	expression tag
Thr -66	-	expression tag
Pro -65	-	expression tag
Leu -64	-	expression tag
Arg -63	-	expression tag
Arg -62	-	expression tag
Leu -61	-	expression tag
Met -60	-	expression tag
Glu -59	-	expression tag
Ala -58	-	expression tag
Phe -57	-	expression tag
Ala -56	-	expression tag
Lys -55	-	expression tag
Arg -54	-	expression tag
Gln -53	-	expression tag
Gly -52	-	expression tag
Lys -51	-	expression tag
Glu -50	-	expression tag
Met -49	-	expression tag
Asp -48	-	expression tag
Ser -47	-	expression tag
Leu -46	-	expression tag
Arg -45	-	expression tag
Phe -44	-	expression tag
Leu -43	-	expression tag
Tyr -42	-	expression tag
Asp -41	-	expression tag
Gly -40	-	expression tag
Ile -39	-	expression tag
Arg -38	-	expression tag
Ile -37	-	expression tag
Gln -36	-	expression tag
Ala -35	-	expression tag
Asp -34	-	expression tag
Gln -33	-	expression tag
Thr -32	-	expression tag
Pro -31	-	expression tag
Glu -30	-	expression tag
Asp -29	-	expression tag
Leu -28	-	expression tag
Asp -27	-	expression tag
Met -26	-	expression tag
Glu -25	-	expression tag
Asp -24	-	expression tag
Asn -23	-	expression tag
Asp -22	-	expression tag
Ile -21	-	expression tag
Ile -20	-	expression tag
Glu -19	-	expression tag
Ala -18	-	expression tag
His -17	-	expression tag
Arg -16	-	expression tag
Glu -15	-	expression tag
Gln -14	-	expression tag
Ile -13	-	expression tag
Gly -12	-	expression tag
Gly -11	-	expression tag
Thr -10	-	expression tag
Leu -9	-	expression tag
Glu -8	-	expression tag
Ala -7	-	expression tag
Gln -6	-	expression tag
Thr -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	65627.5
Non-Polymers*	Number of molecules	2
	Total formula weight	457.7
All*	Total formula weight	66085.2

*Water molecules are not included.