6OSW
An order-to-disorder structural switch activates the FoxM1 transcription factor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Forkhead box M1 | polymer | 94 | 10515.1 | 1 | UniProt (Q7T2G3) In PDB | Danio rerio (Zebrafish) | Forkhead box M1-like |
| 2 | B | Forkhead box M1 | polymer | 56 | 5950.6 | 1 | UniProt (Q7T2G3) In PDB | Danio rerio (Zebrafish) | Forkhead box M1-like |
Sequence modifications
A: 4 - 88 (UniProt: Q7T2G3)
B: 569 - 623 (UniProt: Q7T2G3)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Glu 2 | - | expression tag |
| Phe 3 | - | expression tag |
| Ala 22 | Leu 19 | engineered mutation |
| - | Glu 22 | deletion |
| - | Ser 23 | deletion |
| - | Asp 24 | deletion |
| - | Leu 25 | deletion |
| - | Gly 26 | deletion |
| - | Cys 27 | deletion |
| - | Asp 28 | deletion |
| - | Glu 29 | deletion |
| - | Ala 30 | deletion |
| - | Asp 31 | deletion |
| - | Gly 32 | deletion |
| - | Thr 33 | deletion |
| - | Arg 34 | deletion |
| - | Cys 35 | deletion |
| - | Lys 36 | deletion |
| - | Thr 37 | deletion |
| - | Thr 38 | deletion |
| - | Ser 39 | deletion |
| - | Thr 40 | deletion |
| - | Gln 41 | deletion |
| - | Ser 42 | deletion |
| Ala 69 | Cys 87 | engineered mutation |
| Ala 86 | Leu 104 | engineered mutation |
| Glu 89 | - | cloning artifact |
| Asn 90 | - | cloning artifact |
| Leu 91 | - | cloning artifact |
| Tyr 92 | - | cloning artifact |
| Phe 93 | - | cloning artifact |
| Gln 94 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 568 | - | cloning artifact |
| Ala 569 | Leu 569 | engineered mutation |
| Ala 571 | Val 571 | engineered mutation |
| Ala 622 | Leu 622 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 16465.7 | |
| All* | Total formula weight | 16465.7 |
