6OQO
CDK6 in complex with Cpd24 N-(5-(6-ethyl-2,6-diazaspiro[3.3]heptan-2-yl)pyridin-2-yl)-5-fluoro-4-(4-methyl-5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a]azepin-3-yl)pyrimidin-2-amine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Cyclin-dependent kinase 6 | polymer | 291 | 33069.1 | 1 | UniProt (Q00534) Pfam (PF00069) In PDB | Homo sapiens (Human) | Cell division protein kinase 6,Serine/threonine-protein kinase PLSTIRE |
2 | A | N-[5-(6-ethyl-2,6-diazaspiro[3.3]heptan-2-yl)pyridin-2-yl]-5-fluoro-4-[(4R)-4-methyl-5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a]azepin-3-yl]pyrimidin-2-amine | non-polymer | 462.6 | 1 | Chemie (N1J) | |||
3 | water | water | 18.0 | 73 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33069.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 462.6 | |
All* | Total formula weight | 33531.6 |