6OQC
Crystal structure of Mcl1 with inhibitor 9
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 157 | 17922.3 | 2 | UniProt (Q07820) Pfam (PF00452) In PDB | Homo sapiens (Human) | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
2 | A, B | (4S,7aR,9aR,10S,11E,15R)-6'-chloro-10-hydroxy-15-methyl-3',4',7a,8,9,9a,10,13,14,15-decahydro-2'H,3H,5H-spiro[1,19-(ethanediylidene)-16lambda~6~-cyclobuta[i][1,4]oxazepino[3,4-f][1,2,7]thiadiazacyclohexadecine-4,1'-naphthalene]-16,16,18(7H,17H)-trione | non-polymer | 585.2 | 2 | Chemie (N0S) | |||
3 | water | water | 18.0 | 299 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 35844.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1170.3 | |
All* | Total formula weight | 37015.0 |