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6OPK

Phosphorylated ERK2 with Vertex-11e

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mitogen-activated protein kinase 1polymer35241003.91UniProt (P63086)
Pfam (PF00069)
Rattus norvegicus (Rat)MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAPK 2
2B
(A)
4-{2-[(2-chloro-4-fluorophenyl)amino]-5-methylpyrimidin-4-yl}-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamidenon-polymer500.41Chemie (390)
3C
(A)
waterwater18.020Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41003.9
Non-Polymers*Number of molecules1
Total formula weight500.4
All*Total formula weight41504.3
*Water molecules are not included.

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PDB entries from 2025-12-17

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