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6OP9

HER3 pseudokinase domain bound to bosutinib

Replaces:  4OTW
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Receptor tyrosine-protein kinase erbB-3polymer32836941.91UniProt (P21860)
Pfam (PF07714)
Homo sapiens (Human)Proto-oncogene-like protein c-ErbB-3,Tyrosine kinase-type cell surface receptor HER3
2B
(A)
4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrilenon-polymer530.41Chemie (DB8)
3C
(A)
waterwater18.089Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight36941.9
Non-Polymers*Number of molecules1
Total formula weight530.4
All*Total formula weight37472.4
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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