6OOS
HIV-1 Protease NL4-3 L90M Mutant in complex with darunavir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (B, D, A, C) | NL4-3 PROTEASE | polymer | 99 | 10849.9 | 4 | UniProt (Q3HWC9) Pfam (PF00077) UniProt (by SIFTS) (P12497) | Human immunodeficiency virus 1 | |
| 2 | E, F, H, I, J... (B, D, A, C) | SULFATE ION | non-polymer | 96.1 | 11 | Chemie (SO4) | |||
| 3 | G, L (A, C) | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE | non-polymer | 547.7 | 2 | Chemie (017) | |||
| 4 | R, S, T, U (B, D, A, C) | water | water | 18.0 | 340 | Chemie (HOH) |
Sequence modifications
B, D, A, C: 1 - 99 (UniProt: Q3HWC9)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 7 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 43399.5 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2152.0 | |
| All* | Total formula weight | 45551.5 |
