6OMZ
Crystal Structure of Dihydropteroate synthase from Mycobacterium smegmatis with bound 6-hydroxymethylpterin-monophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydropteroate synthase | polymer | 293 | 30517.6 | 1 | UniProt (A0A2U9PYL8) Pfam (PF00809) | Mycobacterium smegmatis (strain MKD8) | DHPS,Dihydropteroate pyrophosphorylase |
| 2 | B, E (A) | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
| 3 | C (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | D (A) | PTERIN-6-YL-METHYL-MONOPHOSPHATE | non-polymer | 273.1 | 1 | Chemie (PMM) | |||
| 5 | F, G, H, I, J... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 6 | N (A) | water | water | 18.0 | 323 | Chemie (HOH) |
Sequence modifications
A: 1 - 285 (UniProt: A0A2U9PYL8)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| Ala -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Glu 282 | Gly 282 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30517.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1232.1 | |
| All* | Total formula weight | 31749.7 |
