6OKN

OX40R (TNFRSF4) bound to Fab 1A7

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Fab 1A7 heavy chain	polymer	225	24206.1	2		Homo sapiens (human)
2	B, D	Fab 1A7 light chain	polymer	214	23531.1	2		Homo sapiens (human)
3	E, R	Tumor necrosis factor receptor superfamily member 4	polymer	163	17697.9	2	UniProt (P43489) Pfam (PF00020) In PDB	Homo sapiens (Human)	ACT35 antigen,OX40L receptor,TAX transcriptionally-activated glycoprotein 1 receptor
4	A, B, D	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	3	Chemie (EPE)
5		water	water		18.0	3	Chemie (HOH)

Sequence modifications

E, R: 29 - 170 (UniProt: P43489)

PDB	External Database	Details
Met 8	-	initiating methionine
Gly 9	-	expression tag
Ser 10	-	expression tag
Ser 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
Ser 18	-	expression tag
Ser 19	-	expression tag
Gly 20	-	expression tag
Leu 21	-	expression tag
Val 22	-	expression tag
Pro 23	-	expression tag
Arg 24	-	expression tag
Gly 25	-	expression tag
Ser 26	-	expression tag
His 27	-	expression tag
Met 28	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	130870.1
Non-Polymers*	Number of molecules	3
	Total formula weight	714.9
All*	Total formula weight	131585.0

*Water molecules are not included.