6OJQ
Monomeric kinesin-1 motor domain in no-nucleotide state bound to GMPCPP-stabilized microtubule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Tubulin beta-2B chain | polymer | 426 | 47825.9 | 1 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | |
| 2 | B (A) | Tubulin alpha-1B chain | polymer | 437 | 48665.0 | 1 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 3 | C (K) | Kinesin-1 heavy chain | polymer | 317 | 35445.8 | 1 | UniProt (P33176) Pfam (PF00225) | Homo sapiens (Human) | Conventional kinesin heavy chain,Ubiquitous kinesin heavy chain,UKHC |
| 4 | D (B) | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | non-polymer | 521.2 | 1 | Chemie (G2P) | |||
| 5 | E, G (B, A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | F (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) |
Sequence modifications
B: 1 - 436 (UniProt: Q6B856)
K: 8 - 324 (UniProt: P33176)
| PDB | External Database | Details |
|---|---|---|
| Ala 57 | Thr 55 | conflict |
| Val 172 | Met 170 | conflict |
| Ala 298 | Ser 296 | conflict |
| Val 318 | Ile 316 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 65 | Cys 65 | conflict |
| Ala 168 | Cys 168 | conflict |
| Ser 174 | Cys 174 | conflict |
| Ala 294 | Cys 294 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 131936.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1093.0 | |
| All* | Total formula weight | 133029.7 |
