6OIL

Crystal structure of human VISTA extracellular domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	V-type immunoglobulin domain-containing suppressor of T-cell activation	polymer	168	19047.2	1	UniProt (Q9H7M9) Pfam (PF07686)	Homo sapiens (Human)	Platelet receptor Gi24,Stress-induced secreted protein-1,Sisp-1,V-set domain-containing immunoregulatory receptor,V-set immunoregulatory receptor
2	B, C (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
3	D (A)	water	water		18.0	41	Chemie (HOH)

Sequence modifications

A: 1 - 162 (UniProt: Q9H7M9)

PDB	External Database	Details
Gln 59	Asn 91	engineered mutation
Gln 76	Asn 108	engineered mutation
Glu 155	Asp 187	engineered mutation
Gln 158	Asn 190	engineered mutation
His 163	-	expression tag
His 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag
His 167	-	expression tag
His 168	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	19047.2
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	19489.6

*Water molecules are not included.