6OGK

MeCP2 MBD in complex with DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Methyl-CpG-binding protein 2	polymer	99	11269.6	1	UniProt (P51608) Pfam (PF01429)	Homo sapiens (Human)	MeCp2
2	B (D)	DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*CP*TP*CP*CP*G)-3')	polymer	12	3597.4	1		synthetic construct
3	C (C)	DNA (5'-D(*CP*GP*GP*AP*GP*TP*GP*TP*AP*GP*GP*C)-3')	polymer	12	3743.4	1		synthetic construct
4	D, E, F, G, H... (A, D, C)	UNKNOWN LIGAND	non-polymer			17	Chemie (UNX)
5	N (A)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
6	V, W, X (A, D, C)	water	water		18.0	56	Chemie (HOH)

Sequence modifications

A: 77 - 167 (UniProt: P51608)

PDB	External Database	Details
Ala 168	-	expression tag
Ala 169	-	expression tag
His 170	-	expression tag
His 171	-	expression tag
His 172	-	expression tag
His 173	-	expression tag
His 174	-	expression tag
His 175	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	18610.4
Non-Polymers*	Number of molecules	18
	Total formula weight	40.1
All*	Total formula weight	18650.5

*Water molecules are not included.